
ANTIGEN TEST KITS
SARS-COV-2 (ELISA)
COVID-19 RAPID TEST CASSETTE
The World Health Organization (WHO) on March 11 declared COVID-19 a pandemic, pointing to the over million cases of the corona virus illness in over 110 countries and territories around the world and the sustained risk of further global spread. To stop further global spread of the virus, the world needs a screening test that is fast and reliable. We started to develop a rapid test cassette against the COVID-19.
HOUGH Pharma is proud to announce that we are one of the first companies with a rapid test for COVID-19 IgG/IgM. Our product is made with FDA/CE/TGA mark in order to to fulfill highest USA/European/Australian standards . Now worldwide our product is being used to screen patients for the coronavirus.
Video Instructions
HOW TO USE
Symptoms
OF COVID-19 PATIENT

Testing Technique
COMPARISON
Advantages
Disadvantages
PCR Detection
Mature technique
Can be used for early diagnosis
Complex operation and high cost
High false negative rate
Antibody Detection
Simple operation
Low cost
Cannot be used for early
diagnosis
Antigen Detection
(Nasopharynx swab)
Early diagnosis
Easy operation
Less sensitive than nucleic
acid testing
False negative question
Main Mechanism of
ANTIGEN IN BLOOD
When SARS-CoV-2 invades the lung cells it will express a large amount of self protein to reassemble the virus particles causing cell damage and forming inflammation. The virus protein expressed in excess and the virus protein released from the disintegration of virus particles killed by the body in the lesions will enter the blood circulation through the vessel wall with increased permeability due to inflammation in the lesions.

Main Mechanism of
REDUCTION & ELMINATION
-
The virus antigen will stimulate the patient's body to produce the corresponding antibody, and the antibody produced by the body will produce the specific combination with the corresponding antigen, forming the antigen antibody immune complex to be cleared by the body's immune system. As the amount of antibody produced by the patient increases gradually, the amount of antigen cleared will also increase synchronously.
-
With the activation of the immune system, the ability of killing virus is enhanced, the viral load in the body will gradually decrease, and the production of virus and blood antigen will gradually decrease.

Schematic Diagram
ANTIGEN & ANTIBODY CHANGES IN BLOOD

Significance of Combined Detection
OF ANTIGEN & ANTIBODY IN BLOOD
-
The detection of antigens in blood can effectively make up for the "window period" of antibody detection.
-
The detection of antibody in blood can avoid the problem that antigen can not be detected in the middle and later stage of infection.
-
The combined detection of antigen and antibody in blood can verify each other at different disease stages, and provide complete serological evidence for the diagnosis of COVID-19.
Test Sensitivity
SARS-COV-2 ANTIGEN
Cut-off value=2.97pg/mL
Group
1
2
3
SUM
Days from onset
≤ 3
4 ~ 7 days
8 ~ 14 days
/
Total number of samples
30
38
28
96
Number of antigen positive samples
32
38
31
101
Sensitivity
93.4%
100%
90.3%
95.0%
-
Sample source: PCR confirmed COVID-19 patients serum samples